WebAbstract. Iron–sulfur clusters are ubiquitous and ancient prosthetic groups that are present in all kingdoms of life. They are flexible in terms of coordination and redox properties. The … WebOct 8, 2024 · show that thousands of novel binding sites for iron-sulfur (Fe-S) clusters and zinc ions can be identified ... sensing iron and oxygen [10-12], while Zn binding is …
Iron-Sulfur Clusters: Nature
Iron–sulfur clusters are molecular ensembles of iron and sulfide. They are most often discussed in the context of the biological role for iron–sulfur proteins, which are pervasive. Many Fe–S clusters are known in the area of organometallic chemistry and as precursors to synthetic analogues of the biological clusters (see Figure). It is believed that the last universal common an… WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) greenwood county ks sheriff\\u0027s office
The iron-sulfur cluster is essential for DNA binding by human DNA ...
Webthan a [2Fe-2S] cluster. The site-directed mutation experi-ments suggest that the four cysteine residues are involved in the ligation of this [4Fe-4S] cluster. This iron-sulfur cluster has a unique feature, very high sensitivity to oxygen exposure, which has not been observed on other EPR-detectable iron-sulfur clusters in NDH-1/complex I. WebIron-sulfur clusters are perfect for this task, since they form a unique delocalized system for storing an electron that may be tuned by the surrounding amino acids in a protein. Two types of clusters are particularly common: a square arrangement of two irons and two sulfurs, and a distorted cube composed of four irons and four sulfurs. WebAbstract Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene … greenwood county ks sales tax